HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → (RS)-2-[2-phenyl-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| Product | (RS)-2-[2-phenyl-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester | HCID 86629005 | 95.2% |
Reaction Steps
The title compound (7.07 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (5.0 g) and 2-bromoacetophenone (4.18 g) according to the method of description 36.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423052B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-a69345c2ff894388ba7cfbf63ca39edd |
| Source note | uspto-grants-2008_09 |