2-Amino-5-(2-fluorophenyl)thiophene-3-carboxamide → 5-(2-Fluorophenyl)-2-{[6-(morpholin-4-ylmethyl)pyridin-2-yl]-amino}thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:7]1.[NH2:15][c:16]1[s:17][c:18](-[c:24]2[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]2)[cH:19][c:20]1[C:21](=[O:22])[NH2:23]>>[c:2]1([NH:15][c:16]2[s:17][c:18](-[c:24]3[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]3)[cH:19][c:20]2[C:21](=[O:22])[NH2:23])[cH:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-448a4f8bd2b84e318b3291809e2918f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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