N-bromobutanimide → HCID 67158247, compound

HRID 30196Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:12][C:11]([CH3:13])=[N:10][C:9]=2[C:14]([N:16]2[CH2:20][CH2:19][CH2:18][C@H:17]2[CH2:21][C:22]2[O:23][CH:24]=[C:25]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[N:26]=2)=[O:15])=[CH:4][CH:3]=1.[Br:33]N1C(=O)CCC1=O>>[Br:33][C:24]1[O:23][C:22]([CH2:21][C@@H:17]2[CH2:18][CH2:19][CH2:20][N:16]2[C:14]([C:9]2[N:10]=[C:11]([CH3:13])[S:12][C:8]=2[C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)=[O:15])=[N:26][C:25]=1[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1

Participants

Reactant 2

HCID 67184N-bromobutanimide

HCID 67157873HCID 67157873, compound

Product 1

HCID 67158247HCID 67158247, compoundYield 74.8%

Procedure

The title compound (0.066 g) was prepared by treating the compound of example 172 (0.075 g) with N-bromosuccinimide (0.030 g) according to the method of example 164.

Sources & evidence

ORD record: ord-5ead924051164a3c806c3b86b87d4e6d
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423052B2

Reaction notes

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