Ethyl bromoacetate → Ethyl 10-hydroxy-5,5-dimethyl-8-(1,2-dimethylheptyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine-2-acetate

HRID 302019Notes

Reaction equation

HRID 302019 reaction equation
[Br:27][CH2:28][C:29](=[O:30])[O:31][CH2:32][CH3:33].[OH:1][c:2]1[cH:3][c:4]([CH:18]([CH:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH3:25])[CH3:26])[cH:5][c:6]2[c:7]1[C:8]1=[C:13]([CH2:12][CH2:11][NH:10][CH2:9]1)[C:14]([CH3:16])([CH3:17])[O:15]2>>[OH:1][c:2]1[cH:3][c:4]([CH:18]([CH:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH3:25])[CH3:26])[cH:5][c:6]2[c:7]1[C:8]1=[C:13]([CH2:12][CH2:11][N:10]([CH2:28][C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:9]1)[C:14]([CH3:16])([CH3:17])[O:15]2

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 2135435H-(1)Benzopyrano(4,3-c)pyridine, 1,2,3,4-tetrahydro-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-

Product 1

HCID 21321136Ethyl 10-hydroxy-5,5-dimethyl-8-(1,2-dimethylheptyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine-2-acetate

Sources & evidence

ORD record
ord-15f1a9390c0e4ed2a75ceab0af225bbc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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