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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 302185Generated: October 30, 2026

Hydrochloric Acid → N-{(1RS,2SR)-2-hydroxy-2-(4-hydroxyphenyl)-1-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]ethyl}-6,7-dihydro-5H-benzo[a][7]annulene-1-carboxamide

https://huagongshe.com/reaction/302185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant4-{(1RS,2SR)-2-amino-1-hydroxy-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]propyl}phenolHCID 22262002—
Reactant6,7-dihydro-5H-benzo[a]cycloheptene-1-carboxylic acidHCID 22262010—
ProductN-{(1RS,2SR)-2-hydroxy-2-(4-hydroxyphenyl)-1-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]ethyl}-6,7-dihydro-5H-benzo[a][7]annulene-1-carboxamideHCID 22262226—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-565d11d77afc4212b3812d2d8a049a7e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)