Ethanol → tert-Butyl 4-(5-nitropyridine-2-ylamino)piperidine-1-carboxylate

HRID 302262Notes

Reaction equation

HRID 302262 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH2:14])[CH2:12][CH2:13]1.[CH3:31][CH2:32][OH:33].[Cl:21][c:22]1[n:23][cH:24][c:25]([N+:28](=[O:29])[O-:30])[cH:26][cH:27]1.[Na+:15].[Na+:16].[O-:17][C:18](=[O:19])[O-:20]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:22]2[n:23][cH:24][c:25]([N+:28](=[O:29])[O-:30])[cH:26][cH:27]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ion2×HCID 19660Carbonate IonHCID 783082-Chloro-5-nitropyridineHCID 12682914-Amino-1-Boc-piperidine

Product 1

HCID 53255493tert-Butyl 4-(5-nitropyridine-2-ylamino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-33f92e9c8b1a4bf9a3fec99979fba729
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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