Sodium ion → N-benzyl-4-methyl-2-[5-(3-phenylprop-1-enyl)pyrazin-2-yl]-1,3-thiazole-5-carboxamide

HRID 302338Notes

Reaction equation

HRID 302338 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:23])[n:13][c:14](-[c:16]2[n:17][cH:18][c:19]([Br:22])[n:20][cH:21]2)[s:15]1.[CH3:43][O:44][CH3:45].[Na+:28].[Na+:29].[OH2:42].[c:30]1([CH2:36][CH:37]=[CH:38][B:39]([OH:40])[OH:41])[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:23])[n:13][c:14](-[c:16]2[n:17][cH:18][c:19]([CH:38]=[CH:37][CH2:36][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[n:20][cH:21]2)[s:15]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 8254Dimethyl EtherHCID 19660Carbonate IonHCID 53399115(3-Phenylprop-1-en-1-yl)boronic acidHCID 594895392-(5-Bromo-pyrazin-2-yl)-4-methyl-thiazole-5-carboxylic acid benzylamide

Product 1

HCID 68489055N-benzyl-4-methyl-2-[5-(3-phenylprop-1-enyl)pyrazin-2-yl]-1,3-thiazole-5-carboxamide

Sources & evidence

ORD record
ord-7cd09844d3e24e2b931f8cf0c4547392
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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