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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 302351Generated: October 25, 2026

3,3-Diphenylpyrrolidine → 3-(2-chloro-4-fluorophenyl)-1-[2-(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)-2-oxoethyl]pyrrolidin-2-one

https://huagongshe.com/reaction/302351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3-DiphenylpyrrolidineHCID 418242—
Reactant5-Fluoro-2,3-dihydro-1H-isoindoleHCID 14795869—
Reactant2-(3,3-Bis(4-fluorophenyl)-2-oxopiperidin-1-yl)acetic acidHCID 67359111—
Reactant2-(3-(2-Chloro-4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acidHCID 67360408—
Product3-(2-chloro-4-fluorophenyl)-1-[2-(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)-2-oxoethyl]pyrrolidin-2-oneHCID 45274508—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-6cfa00d1fa744c859b8cc6223d5f9205
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)