Pyridine → 1-(2-THIOPHENEACETYL)-4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDIN-11-YLIDENE)PIPERIDINE

HRID 302364Notes

Reaction equation

HRID 302364 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:22]1)[CH2:7][CH2:8][c:9]1[c:10]([n:11][cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1.[Cl:38][CH2:39][Cl:40].[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1.[s:29]1[c:30]([CH2:34][C:35](=[O:36])[Cl:37])[cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:22]1)[CH2:7][CH2:8][c:9]1[c:10]([n:11][cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][N:19]([C:35]([CH2:34][c:30]2[s:29][cH:33][cH:32][cH:31]2)=[O:36])[CH2:20][CH2:21]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 124087DesloratadineHCID 1623622-Thiopheneacetyl chloride

Product 1

HCID 226219311-(2-THIOPHENEACETYL)-4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDIN-11-YLIDENE)PIPERIDINE

Sources & evidence

ORD record
ord-a2150cfae5344a728352559d9cc5f5a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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