Acetic Acid → 7-bromo-5-(2-fluorophenyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
Reaction equation
[BH4-:22].[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[C:7]([c:12]1[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]1)=[N:8][CH2:9][CH2:10][NH:11]2.[CH3:20][OH:21].[CH3:24][C:25](=[O:26])[OH:27].[Na+:23]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[CH:7]([c:12]1[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]1)[NH:8][CH2:9][CH2:10][NH:11]2Participants
6
Sources & evidence
- ORD record
- ord-dbabea25228648639438fd3842448fa5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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