2-(5-Bromo-2-chloro-pyrimidin-4-ylamino)-N-methyl-benzamide → 2-[5-Bromo-2-(3-methoxy-5-methyl-6-oxo-5,6,8,9-tetrahydro-7-oxa-5-aza-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

HRID 302661Notes

Reaction equation

HRID 302661 reaction equation
[Br:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[NH:14][CH3:15])[cH:16][cH:17][cH:18][cH:19]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1.[NH2:20][c:21]1[c:22]([O:34][CH3:35])[cH:23][c:24]2[c:25]([cH:33]1)[CH2:26][CH2:27][O:28][C:29](=[O:32])[N:30]2[CH3:31]>>[Br:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[NH:14][CH3:15])[cH:16][cH:17][cH:18][cH:19]2)[n:4][c:5]([NH:20][c:21]2[c:22]([O:34][CH3:35])[cH:23][c:24]3[c:25]([cH:33]2)[CH2:26][CH2:27][O:28][C:29](=[O:32])[N:30]3[CH3:31])[n:6][cH:7]1

Participants

3

Reactant 2

HCID 587484682-(5-Bromo-2-chloro-pyrimidin-4-ylamino)-N-methyl-benzamideHCID 672646482-Amino-3-methoxy-5-methyl-8,9-dihydro-5H-7-oxa-5-aza-benzocyclohepten-6-one

Product 1

HCID 668296322-[5-Bromo-2-(3-methoxy-5-methyl-6-oxo-5,6,8,9-tetrahydro-7-oxa-5-aza-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

Sources & evidence

ORD record
ord-dcd1a782cc0c43a398211fcb623b6433
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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