4-Fluorobenzyl bromide → [2-Fluoro-4-[(4-fluorophenyl)methoxy]phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone
Reaction equation
[F:1][c:2]1[c:3]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[cH:4][cH:5][c:6]([OH:8])[cH:7]1.[F:22][c:23]1[cH:24][cH:25][c:26]([CH2:27][Br:28])[cH:29][cH:30]1>>[F:1][c:2]1[c:3]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[cH:4][cH:5][c:6]([O:8][CH2:27][c:26]2[cH:25][cH:24][c:23]([F:22])[cH:30][cH:29]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-0968e36b4ca940948ee35d5ccdd8ec14
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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