5-chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiophene-2-sulfonamide → 5-[7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Reaction equation
[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15].[OH:26][CH2:27][C:28]([CH3:29])([CH3:30])[NH:31][S:32](=[O:33])(=[O:34])[c:35]1[s:36][c:37]([Cl:40])[cH:38][cH:39]1>>[C:1](#[C:2][c:37]1[s:36][c:35]([S:32]([NH:31][C:28]([CH2:27][OH:26])([CH3:29])[CH3:30])(=[O:33])=[O:34])[cH:39][cH:38]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f613537919ef46a78ae3919684ffaffa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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