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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 303347Generated: October 30, 2026

O-Xylene → [6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(2-methoxy-5-pyridin-2-yl-phenyl)-methanone

https://huagongshe.com/reaction/303347

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-XyleneHCID 7237—
ReactantTriphenylphosphineHCID 11776—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantPalladium ChlorideHCID 24290—
Reactant2-(Tributylstannyl)pyridineHCID 607784—
Reactant(5-Bromo-2-methoxy-phenyl)-[6-(2,4-difluoro-phenylamino)-pyridin-3-yl]-methanoneHCID 22349594—
Product[6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(2-methoxy-5-pyridin-2-yl-phenyl)-methanoneHCID 10112662—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-982e0093f53c4283a9241d3ce602353e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)