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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 303395Generated: October 30, 2026

Tetrahydrofuran → N-{4-[6-Cyano-7-(2-hydroxy-3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy]-2-fluorophenyl}-N'-(4-fluorophenyl)urea

https://huagongshe.com/reaction/303395

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantPyrrolidineHCID 31268—
ReactantN-[4-(6-cyano-7-oxiranylmethoxyquinolin-4-yloxy)-2-fluorophenyl]-N'-(4-fluorophenyl)ureaHCID 22936552—
ProductN-{4-[6-Cyano-7-(2-hydroxy-3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy]-2-fluorophenyl}-N'-(4-fluorophenyl)ureaHCID 67202167—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ef4115a3b4554462b2a5e478ae1dab15
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)