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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 303449Generated: October 26, 2026

4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile → 4-Chloro-2-(difluoromethyl)-1-{2-[(6-fluoro-3-pyridinyl)oxy]ethyl}-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/303449

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrileHCID 24985632—
ReactantPyridine, 5-(2-bromoethoxy)-2-fluoro-HCID 67405380—
Product4-Chloro-2-(difluoromethyl)-1-{2-[(6-fluoro-3-pyridinyl)oxy]ethyl}-1H-indole-5-carbonitrileHCID 24986125—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4f23a69f897148ada0cbefbea49b4773
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)