(4-Chlorophenyl)methyl chloroformate → (2'-{[(4-Chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

HRID 303540Notes

Reaction equation

HRID 303540 reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:23][NH:24][CH2:25][CH3:26])[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:27].[Cl:28][C:29](=[O:30])[O:31][CH2:32][c:33]1[cH:34][cH:35][c:36]([Cl:39])[cH:37][cH:38]1>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:23][N:24]([CH2:25][CH3:26])[C:29](=[O:30])[O:31][CH2:32][c:33]3[cH:34][cH:35][c:36]([Cl:39])[cH:37][cH:38]3)[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:27]

Participants

3

Reactant 2

HCID 13292914(4-Chlorophenyl)methyl chloroformateHCID 66603748(2'-Ethylaminomethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

Product 1

HCID 66607989(2'-{[(4-Chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

Sources & evidence

ORD record
ord-c8056452d58f41dc9b78d2ca77a5f978
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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