Formaldehyde → 7,8-difluoro-4-[3-(2-methoxyethyl)-4-methylpiperazin-1-yl]-10H-thieno[2,3-b][1,5]benzodiazepine
Reaction equation
[C:29]([O:30][BH-:31]([O:32][C:33](=[O:34])[CH3:35])[O:36][C:37](=[O:38])[CH3:39])(=[O:40])[CH3:41].[CH2:27]=[O:28].[Cl:43][CH2:44][Cl:45].[F:1][c:2]1[c:3]([F:26])[cH:4][c:5]2[c:6]([cH:25]1)[NH:7][c:8]1[s:9][cH:10][cH:11][c:12]1[C:13]([N:15]1[CH2:16][CH:17]([CH2:21][CH2:22][O:23][CH3:24])[NH:18][CH2:19][CH2:20]1)=[N:14]2.[Na+:42]>>[F:1][c:2]1[c:3]([F:26])[cH:4][c:5]2[c:6]([cH:25]1)[NH:7][c:8]1[s:9][cH:10][cH:11][c:12]1[C:13]([N:15]1[CH2:16][CH:17]([CH2:21][CH2:22][O:23][CH3:24])[N:18]([CH3:29])[CH2:19][CH2:20]1)=[N:14]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-869aa31906c54e09a9607a6aad080263
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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