Lactic Acid → 1-[4-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-2-hydroxypropan-1-one

HRID 303950Notes

Reaction equation

HRID 303950 reaction equation
[CH3:24][CH:25]([OH:26])[C:27]([OH:28])=[O:29].[Cl:1][c:2]1[n:3][c:4]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1)[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:27]([CH:25]([CH3:24])[OH:26])=[O:28])[CH2:16][CH2:17]1)[s:10]2

Participants

3

Reactant 2

HCID 612Lactic AcidHCID 574940574-(2-Chloro-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-4-yl)morpholine

Product 1

HCID 866235471-[4-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-2-hydroxypropan-1-one

Sources & evidence

ORD record
ord-471489c8fe02477ea9f1069c35ae5f9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…