Cyclooctylamine → 1,3,5-Benzenetricarboxylic acid tris(cyclooctylamide)

Participants

Reaction Conditions

Reaction Steps

4.20 g (33 mmol) of cyclooctylamine and 0.1 g of dry LiCl are added under inert atmosphere to 70 ml of dry NMP and 15 ml of dry pyridine and cooled to 5° C. Then, 2.39 g (9 mmol) of 1,3,5-benzenetricarboxylic acid trichloride are added. The reaction mixture is heated to 75° C. and stirred. After 2 hours the reaction mixture is added to 300 ml of ice water. Customary work-up (recrystallization from N,N-dimethylformamide) gives 1,3,5-benzenetricarboxylic acid tris(cyclooctylamide).

Provenance & Evidence