2-Iodo-4-(trifluoromethyl)phenol → N-(2,4-dimethoxybenzyl)-2,5-difluoro-4-[2-iodo-4-(trifluoromethyl)phenoxy]-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide

HRID 304094Notes

Reaction equation

HRID 304094 reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([F:18])[cH:12][c:13]([F:17])[c:14]([F:16])[cH:15]2)[c:19]2[n:20][cH:21][n:22][s:23]2)[cH:24][cH:25][c:26]([O:28][CH3:29])[cH:27]1.[I:30][c:31]1[c:32]([OH:41])[cH:33][cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]1>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([F:18])[cH:12][c:13]([O:41][c:32]3[c:31]([I:30])[cH:36][c:35]([C:37]([F:38])([F:39])[F:40])[cH:34][cH:33]3)[c:14]([F:16])[cH:15]2)[c:19]2[n:20][cH:21][n:22][s:23]2)[cH:24][cH:25][c:26]([O:28][CH3:29])[cH:27]1

Participants

3

Reactant 2

HCID 115728162-Iodo-4-(trifluoromethyl)phenolHCID 59436583N-(2,4-Dimethoxybenzyl)-2,4,5-trifluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide

Product 1

HCID 59436549N-(2,4-dimethoxybenzyl)-2,5-difluoro-4-[2-iodo-4-(trifluoromethyl)phenoxy]-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide

Sources & evidence

ORD record
ord-1917dc2848a649cb87b89adfaece89ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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