Methanol → 5-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-2,2-dimethylfuran-3(2H)-one

HRID 304174Notes

Reaction equation

HRID 304174 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([C:15]2=[C:16]([c:23]3[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]3)[C:17](=[O:22])[C:18]([CH3:20])([CH3:21])[O:19]2)[cH:13][cH:14]1.[CH3:33][OH:34].[H:31][H:32].[OH-:35].[OH-:36].[Pd+2:37]>>[OH:8][c:9]1[cH:10][cH:11][c:12]([C:15]2=[C:16]([c:23]3[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]3)[C:17](=[O:22])[C:18]([CH3:20])([CH3:21])[O:19]2)[cH:13][cH:14]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 593547815-(4-(benzyloxy)phenyl)-4-(4-methoxyphenyl)-2,2-dimethylfuran-3(2H)-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 593547485-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-2,2-dimethylfuran-3(2H)-one

Sources & evidence

ORD record
ord-0c10bc7d4e0443908736ceddf8068d75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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