6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone → 6-[4-[2-[3-(4-(2-n-Butyloxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3-(2H)-pyridazinone

HRID 304254Notes

Reaction equation

HRID 304254 reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:14][CH2:15][CH:16]2[CH2:17][O:18]2)[cH:19][cH:20]1.[NH2:21][CH2:22][CH2:23][O:24][c:25]1[cH:26][cH:27][c:28]([C:31]2=[N:36][NH:35][C:34](=[O:37])[CH2:33][CH2:32]2)[cH:29][cH:30]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:14][CH2:15][CH:16]([CH2:17][NH:21][CH2:22][CH2:23][O:24][c:25]2[cH:26][cH:27][c:28]([C:31]3=[N:36][NH:35][C:34](=[O:37])[CH2:33][CH2:32]3)[cH:29][cH:30]2)[OH:18])[cH:19][cH:20]1

Participants

3

Reactant 2

HCID 144418666-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinoneHCID 151078111-[4-(2-n-Butyloxyethoxymethyl)phenoxy]-2,3-epoxypropane

Product 1

HCID 151078796-[4-[2-[3-(4-(2-n-Butyloxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3-(2H)-pyridazinone

Sources & evidence

ORD record
ord-e9cb1f8e76ed4536bf0b7f9ec2816104
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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