2-Amino-5-(4-chlorophenyl)thiophene-3-carboxamide → 5-(4-Chlorophenyl)-2-{[6-(1,2-dihydroxy-1-methylethyl)pyridin-2-yl]amino}thiophene-3-carboxamide
Reaction equation
[Br:17][c:18]1[cH:19][cH:20][cH:21][c:22]([C:24]([CH2:25][OH:26])([CH3:27])[OH:28])[n:23]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:18]1[cH:19][cH:20][cH:21][c:22]([C:24]([CH2:25][OH:26])([CH3:27])[OH:28])[n:23]1Participants
3
Sources & evidence
- ORD record
- ord-6a1df6473b334f57a2d690f6c46c189a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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