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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 304407Generated: October 25, 2026

1,2-Dichloroethane → 5-(6-methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide

https://huagongshe.com/reaction/304407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantFormaldehydeHCID 712—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-(3-(trifluoromethyl)phenyl)-1H-indole-1-carboxamideHCID 59394429—
Product5-(6-methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amideHCID 59394597—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-9fe16a1e2f034c078f57435dec75d08c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)