HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 304516Generated: October 26, 2026
Toluene → 1-(2,2-difluoroethyl)-3-[4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
https://huagongshe.com/reaction/304516
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 2,2-Difluoroethanamine | HCID 136274 | — |
| Reactant | 4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]aniline | HCID 67176516 | — |
| Product | 1-(2,2-difluoroethyl)-3-[4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | HCID 87299135 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
| ORD ID | ord-cc66f75af0c5406ba4f2c0ff63be9f65 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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