反应详情

(5-Bromo-pyridin-3-yl)-methanol (1.13 g, 6.00 mmol) was dissolved in CHCI3 (40 mL) and treated with MnO2 (3.60 g). The reaction mixture was heated at reflux temperature for 3 h. The hot reaction mixture was filtered through a pad of diatomaceous earth and the filtrate was concentrated to yield the title compound (0.570 g, 51%).

1. temperatureThe reaction mixture was heated
2. temperatureat reflux temperature for 3 h
3. filtrationThe hot reaction mixture was filtered through a pad of diatomaceous earth
4. concentrationthe filtrate was concentrated