HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-((5-Bromopyridin-3-yl)methyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 5-Bromo-3-pyridinecarboxaldehyde | HCID 2784734 | — |
| Product | 4-((5-Bromopyridin-3-yl)methyl)morpholine | HCID 22390415 | 61% |
Reaction Steps
The title compound was prepared in a similar way as described in Example 18, Step C, using 5-bromo-pyridine-3-carbaldehyde and morpholine. The crude compound was purified (SiO2: 0-3% 2 M NH3 in MeOH/DCM) to provide the title compound (61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423147B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-fa162b65c69e4dc3b185bf027fd7d8b4 |
| Source note | uspto-grants-2008_09 |