HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → N-((6-Bromopyridin-2-yl)methyl)-2-methoxyethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | 6-Bromopyridine-2-carbaldehyde | HCID 2757009 | — |
| Product | N-((6-Bromopyridin-2-yl)methyl)-2-methoxyethanamine | HCID 57967278 | 94% |
Reaction Steps
The title compound was prepared in a manner similar to that described in Example 18, Step C, using 6-bromo-pyridine-2-carbaldehyde (0.275 g, 1.48 mmol) and 2-methoxy-ethylamine (0.111 g, 1.48 mmol). The crude product was purified (SiO2: 0-5% MeOH/DCM) to yield the title compound (0.34 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423147B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-96df5a28feab40beb5646f92a9e28476 |
| Source note | uspto-grants-2008_09 |