4-(Pyrrolidin-3-yl)morpholine → (3-morpholin-4-ylpyrrolidin-1-yl)-[8-(1H-pyrazol-4-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-2-yl]methanone

HRID 304807Notes

Reaction equation

HRID 304807 reaction equation
[NH:23]1[CH2:24][CH:25]([N:28]2[CH2:29][CH2:30][O:31][CH2:32][CH2:33]2)[CH2:26][CH2:27]1.[nH:1]1[n:2][cH:3][c:4](-[c:6]2[cH:7][c:8]3[c:9]([cH:21][cH:22]2)-[c:10]2[n:11][c:12]([C:18](=[O:19])[OH:20])[s:13][c:14]2[CH2:15][CH2:16][O:17]3)[cH:5]1>>[nH:1]1[n:2][cH:3][c:4](-[c:6]2[cH:7][c:8]3[c:9]([cH:21][cH:22]2)-[c:10]2[n:11][c:12]([C:18](=[O:19])[N:23]4[CH2:24][CH:25]([N:28]5[CH2:29][CH2:30][O:31][CH2:32][CH2:33]5)[CH2:26][CH2:27]4)[s:13][c:14]2[CH2:15][CH2:16][O:17]3)[cH:5]1

Participants

3

Reactant 2

HCID 146273734-(Pyrrolidin-3-yl)morpholineHCID 582038838-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid

Product 1

HCID 67061758(3-morpholin-4-ylpyrrolidin-1-yl)-[8-(1H-pyrazol-4-yl)-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-2-yl]methanone

Sources & evidence

ORD record
ord-56a086d88d604a0bb60dcb76cd5b9b70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…