Morpholine → HCID 44515773, compound
Reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[N:9][C:8]([CH:11]=O)=[CH:7][N:6]=1)=[O:4].[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>>[CH3:1][O:2][C:3]([C:5]1[CH:10]=[N:9][C:8]([CH2:11][N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:7][N:6]=1)=[O:4]Participants
3
Procedure
The title compound was prepared in a manner similar to that described in Example 23, Step C, using 5-formyl-pyrazine-2-carboxylic acid methyl ester (0.78 g, 4.7 mmol) and morpholine (0.44 g, 5.2 mmol).
Sources & evidence
- ORD record
- ord-0dd76f23e24d4ff18fead4a1e1986f71
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07423147B2
Reaction notes
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