Acetaldehyde → N-(5-Bromo-pyridin-2-yl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-4-[4-(ethyl-propyl-amino)-phenylsulfanyl]-benzamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[cH:11][c:12]([NH:27][c:28]3[c:29]4[c:30]([n:31][cH:32][n:33]3)[n:34][c:35]([CH:38]([CH3:39])[CH3:40])[cH:36][cH:37]4)[c:13]([S:16][c:17]3[cH:18][cH:19][c:20]([NH:23][CH2:24][CH2:25][CH3:26])[cH:21][cH:22]3)[cH:14][cH:15]2)=[O:41])[n:6][cH:7]1.[C:42]([CH3:43])([O:44][BH-:45]([O:46][C:47](=[O:48])[CH3:49])[O:50][C:51](=[O:52])[CH3:53])=[O:54].[CH3:59][OH:60].[CH:56](=[O:57])[CH3:58].[Cl:61][CH2:62][Cl:63].[Na+:55]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[cH:11][c:12]([NH:27][c:28]3[c:29]4[c:30]([n:31][cH:32][n:33]3)[n:34][c:35]([CH:38]([CH3:39])[CH3:40])[cH:36][cH:37]4)[c:13]([S:16][c:17]3[cH:18][cH:19][c:20]([N:23]([CH2:24][CH2:25][CH3:26])[CH2:42][CH3:43])[cH:21][cH:22]3)[cH:14][cH:15]2)=[O:41])[n:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-653257f96c7c46dfac62abd25cf6f4c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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