5-(2-(Methylthio)ethoxy)pyrimidin-2-amine → Ethyl 2-(trans-4-((ethyl(2-(((5-(2-(methylthio)ethoxy)pyrimidin-2-yl)amino)methyl)-4-(trifluoromethyl)phenyl)amino)methyl)cyclohexyl)acetate
Reaction equation
[CH3:29][S:30][CH2:31][CH2:32][O:33][c:34]1[cH:35][n:36][c:37]([NH2:40])[n:38][cH:39]1.[CH:1](=[O:2])[c:3]1[c:4]([N:13]([CH2:14][CH3:15])[CH2:16][CH:17]2[CH2:18][CH2:19][CH:20]([CH2:23][C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:21][CH2:22]2)[cH:5][cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1>>[CH2:1]([c:3]1[c:4]([N:13]([CH2:14][CH3:15])[CH2:16][CH:17]2[CH2:18][CH2:19][CH:20]([CH2:23][C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:21][CH2:22]2)[cH:5][cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)[NH:40][c:37]1[n:36][cH:35][c:34]([O:33][CH2:32][CH2:31][S:30][CH3:29])[cH:39][n:38]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-de50167097344cbaaf4c3c44eb5a2a7f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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