Acetic Acid → 5-benzyloxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamino]-ethyl}-2,2-dimethyl-4H-benzo[1,4]oxazin-3-one
Reaction equation
[BH4-:1].[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[O:10][c:11]1[cH:12][cH:13][c:14]([CH:24]([CH:25]=[N:26][C:27]([CH2:28][c:29]2[cH:30][cH:31][c:32]([O:35][CH3:36])[cH:33][cH:34]2)([CH3:37])[CH3:38])[OH:39])[c:15]2[c:16]1[NH:17][C:18](=[O:23])[C:19]([CH3:21])([CH3:22])[O:20]2.[CH3:40][C:41](=[O:42])[CH3:43].[CH3:44][C:45](=[O:46])[OH:47].[CH3:48][CH2:49][OH:50].[Na+:2].[OH2:51]>>[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[O:10][c:11]1[cH:12][cH:13][c:14]([CH:24]([CH2:25][NH:26][C:27]([CH2:28][c:29]2[cH:30][cH:31][c:32]([O:35][CH3:36])[cH:33][cH:34]2)([CH3:37])[CH3:38])[OH:39])[c:15]2[c:16]1[NH:17][C:18](=[O:23])[C:19]([CH3:21])([CH3:22])[O:20]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0c28c0ec5fc54f4693d225bccabdca33
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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