4-Fluorophenylacetyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl (4-fluorophenyl)acetate
Reaction equation
[F:24][c:25]1[cH:26][cH:27][c:28]([CH2:31][C:32](=[O:33])[Cl:34])[cH:29][cH:30]1.[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][c:14]([NH:18][C:19]([CH:20]([CH3:21])[CH3:22])=[O:23])[cH:15][cH:16][cH:17]2)[CH2:10][CH2:11]1>>[O:1]([CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][c:14]([NH:18][C:19]([CH:20]([CH3:21])[CH3:22])=[O:23])[cH:15][cH:16][cH:17]2)[CH2:10][CH2:11]1)[C:32]([CH2:31][c:28]1[cH:27][cH:26][c:25]([F:24])[cH:30][cH:29]1)=[O:33]Participants
3
Sources & evidence
- ORD record
- ord-5b3ed60c8c4549e4bf0079fd6c74d220
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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