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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 305325Generated: October 30, 2026

Water → 2-(3,5-Difluoro-phenoxy)-N-[4-(1-hydroxy-1-methyl-ethyl)-benzyl]-nicotinamide

https://huagongshe.com/reaction/305325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant2-[4-(Aminomethyl)phenyl]propan-2-olHCID 10154211—
Reactant2-(3,5-Difluoro-phenoxy)-nicotinic acidHCID 22612199—
Product2-(3,5-Difluoro-phenoxy)-N-[4-(1-hydroxy-1-methyl-ethyl)-benzyl]-nicotinamideHCID 22612170—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-70705118dc354e778334525534efc5d8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)