2-Bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine → 1-[(5-Amino-2,3-dihydro-2,4,6,7-tetramethylbenzofuran-2-yl)methyl]-N-[bis(4-methoxyphenyl)methyl]-4-piperidinamine

HRID 305400Notes

Reaction equation

HRID 305400 reaction equation
[Br:1][CH2:2][C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1.[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22]([CH:25]([NH:26][CH:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[c:33]2[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]2)[cH:23][cH:24]1>>[CH2:2]([C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1)[N:30]1[CH2:29][CH2:28][CH:27]([NH:26][CH:25]([c:22]2[cH:21][cH:20][c:19]([O:18][CH3:17])[cH:24][cH:23]2)[c:33]2[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]2)[CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 108505902-Bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamineHCID 22111110N-[bis(4-methoxyphenyl)methyl]-4-piperidinamine

Product 1

HCID 221111111-[(5-Amino-2,3-dihydro-2,4,6,7-tetramethylbenzofuran-2-yl)methyl]-N-[bis(4-methoxyphenyl)methyl]-4-piperidinamine

Sources & evidence

ORD record
ord-3cdc72abaaa74db3ac09466f55b2b621
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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