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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 305950Generated: October 30, 2026

Dimethylformamide → 6-(2,4-Dichloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide

https://huagongshe.com/reaction/305950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant1-Amino-2-cyclopropylpropan-2-olHCID 21109692—
Reactant6-(2,4-Dichloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acidHCID 68801087—
Product6-(2,4-Dichloro-phenyl)-5-(2-methoxy-ethoxy)-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amideHCID 86616973—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-d61ed703ba6f422ba6c8916eb6dc7f94
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)