HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-(2-Dimethylamino-ethoxy)-5-pyridin-2-yl-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 4-(2-Dimethylamino-ethoxy)-3-formyl-benzeneboronic acid | HCID 85888855 | — |
| Product | 2-(2-Dimethylamino-ethoxy)-5-pyridin-2-yl-benzaldehyde | HCID 85888875 | 40% |
Reaction Steps
General procedure G using 4-(2-dimethylamino-ethoxy)-3-formyl-benzeneboronic acid and 2-bromo-pyridine gave the title product as yellow oil in 40% yield. 1H-NMR (CDCl3) δ 10.47 (s, 1H), 8.60(dt, 1H), 8.34 (d, 1H), 8.26 (dd, 1H), 7.69-7.67 (m, 2H), 7.17-7.14 (m, 1H), 7.05 (d, 1H), 4.24 (t, 2H), 2.83 (t, 2H), 2.36 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423181B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-baa2a12fddac400698f89e2fa85b83d6 |
| Source note | uspto-grants-2008_09 |