反应详情

Then, 44 g of 2-octylbenzofuran was dissolved in 440 ml of ethanol. To the solution 35 g of 10%-palladium-carbon was added to effect catalytic reduction for 3 hours sunder normal pressure. After the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to obtain a residue. The residue was purified by silica gel column chromatography (eluent:hexane) to obtain 42 g of liquid 2-octylcoumaran (Yield: 94.6%).

1. customfor 3 hours
2. customAfter the reaction
3. customthe catalyst was removed by filtration
4. concentrationthe filtrate was concentrated under reduced pressure
5. customto obtain a residue
6. customThe residue was purified by silica gel column chromatography (eluent:hexane)