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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 306303Generated: October 30, 2026

Potassium Cation → 5-Chloro-N-[4-(cyano-dimethyl-methyl)-benzyl]-2-(4-fluoro-phenoxy)-nicotinamide

https://huagongshe.com/reaction/306303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
ReactantTin tetrachlorideHCID 24287—
ReactantFluoride IonHCID 28179—
ReactantTrimethylsilyl cyanideHCID 82115—
Reactant5-Chloro-2-(4-fluoro-phenoxy)-N-[4-(1-hydroxy-1-methyl-ethyl)-benzyl]-nicotinamideHCID 58915187—
Product5-Chloro-N-[4-(cyano-dimethyl-methyl)-benzyl]-2-(4-fluoro-phenoxy)-nicotinamideHCID 17832833—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-b21a94b393414a38a19c889b466e6649
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)