Methanol → trans-4-(2,5-dimethyl-4-(4-(5-methyl-1H-pyrazol-3-ylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)cyclohexanol
Reaction equation
[BH4-:34].[CH3:1][c:2]1[c:3]([CH:27]2[CH2:28][CH2:29][C:30](=[O:33])[CH2:31][CH2:32]2)[cH:4][c:5]([CH3:26])[c:6]([NH:8][c:9]2[n:10][cH:11][c:12]([C:22]([F:23])([F:24])[F:25])[c:13]([NH:15][c:16]3[n:17][nH:18][c:19]([CH3:21])[cH:20]3)[n:14]2)[cH:7]1.[CH3:36][OH:37].[Na+:35]>>[CH3:1][c:2]1[c:3]([CH:27]2[CH2:28][CH2:29][CH:30]([OH:33])[CH2:31][CH2:32]2)[cH:4][c:5]([CH3:26])[c:6]([NH:8][c:9]2[n:10][cH:11][c:12]([C:22]([F:23])([F:24])[F:25])[c:13]([NH:15][c:16]3[n:17][nH:18][c:19]([CH3:21])[cH:20]3)[n:14]2)[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9c69e349c169461eb113a4c15f580d63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…