Ethanol → 1-(3-aminopropyl)-5-fluoro-3-(4-methoxyphenyl)-8-propoxy-1H-quinolin-4-one

HRID 306509Notes

Reaction equation

HRID 306509 reaction equation
[CH3:42][CH2:43][OH:44].[F:4][c:5]1[c:6]2[c:7](=[O:41])[c:8](-[c:33]3[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]3)[cH:9][n:10]([CH2:19][CH2:20][CH2:21][N:22]3[C:23](=[O:24])[c:25]4[c:26]([cH:27][cH:28][cH:29][cH:30]4)[C:31]3=[O:32])[c:11]2[c:12]([O:15][CH2:16][CH2:17][CH3:18])[cH:13][cH:14]1.[NH2:2][NH2:3].[OH2:1]>>[F:4][c:5]1[c:6]2[c:7](=[O:41])[c:8](-[c:33]3[cH:34][cH:35][c:36]([O:39][CH3:40])[cH:37][cH:38]3)[cH:9][n:10]([CH2:19][CH2:20][CH2:21][NH2:22])[c:11]2[c:12]([O:15][CH2:16][CH2:17][CH3:18])[cH:13][cH:14]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 584924242-{3-[5-fluoro-3-(4-methoxyphenyl)-4-oxo-8-propoxy-4H-quinolin-1-yl]propyl}isoindole-1,3-dione

Product 1

HCID 584925271-(3-aminopropyl)-5-fluoro-3-(4-methoxyphenyl)-8-propoxy-1H-quinolin-4-one

Sources & evidence

ORD record
ord-6500eb03d62c412386191a2d25b5803e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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