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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 306580Generated: October 25, 2026

Acetic Acid → (9-(3-(2-(tert-Butyldimethylsilyloxy)-1-fluoroethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone

https://huagongshe.com/reaction/306580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant(2-Isopropylthiazol-4-yl)-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanoneHCID 57989152—
Reactant3-(2-(tert-Butyldimethylsilyloxy)-1-fluoroethyl)benzaldehydeHCID 57989201—
Product(9-(3-(2-(tert-Butyldimethylsilyloxy)-1-fluoroethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanoneHCID 57989307—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-c61f0c7b418d46af8b09f40fa436ccbe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)