Dichloromethane → 2-(Chloromethyl)-6-(trifluoromethyl)pyridine

HRID 306597Notes

Reaction equation

[Cl:17][CH2:18][Cl:19].[F:1][C:2]([c:3]1[cH:4][cH:5][cH:6][c:7]([CH2:9][OH:10])[n:8]1)([F:11])[F:12].[S:13]([Cl:14])([Cl:15])=[O:16]>>[F:1][C:2]([c:3]1[cH:4][cH:5][cH:6][c:7]([CH2:9][Cl:15])[n:8]1)([F:11])[F:12]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 14761464[6-(Trifluoromethyl)pyridin-2-yl]methanol

Product 1

HCID 673570732-(Chloromethyl)-6-(trifluoromethyl)pyridine

Sources & evidence

ORD record: ord-25d6119cb287440288f0c498438eea04
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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