O-p-Chlorophenyl chlorothioformate → 5-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-butoxy}-2,3-dihydro-indole-1-carbothioic acid O-(4-chloro-phenyl)ester

HRID 306839Notes

Reaction equation

HRID 306839 reaction equation
[Cl:21][c:22]1[cH:23][cH:24][c:25]([O:28][C:29](=[S:30])[Cl:31])[cH:26][cH:27]1.[NH:1]1[CH2:2][CH2:3][c:4]2[cH:5][c:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][N:15]([CH2:16][CH2:17][OH:18])[CH2:19][CH3:20])[cH:7][cH:8][c:9]21>>[N:1]1([C:29]([O:28][c:25]2[cH:24][cH:23][c:22]([Cl:21])[cH:27][cH:26]2)=[S:30])[CH2:2][CH2:3][c:4]2[cH:5][c:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][N:15]([CH2:16][CH2:17][OH:18])[CH2:19][CH3:20])[cH:7][cH:8][c:9]21

Participants

3

Reactant 2

HCID 70306O-p-Chlorophenyl chlorothioformateHCID 219665812-{[4-(2,3-Dihydro-1H-indol-5-yloxy)-butyl]-ethyl amino}-ethanol

Product 1

HCID 865870125-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-butoxy}-2,3-dihydro-indole-1-carbothioic acid O-(4-chloro-phenyl)ester

Sources & evidence

ORD record
ord-faac5ce8cf43436b9986dbbbe87f6b39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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