2-(Bromomethyl)tetrahydro-2H-pyran → 1'-(2,1,3-benzoxadiazol-5-ylmethyl)-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

HRID 306888Notes

Reaction equation

HRID 306888 reaction equation
[Br:12][CH2:13][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][O:19]1.[Br:1][CH2:2][c:3]1[cH:4][c:5]2[c:6]([n:7][o:8][n:9]2)[cH:10][cH:11]1.[NH:20]1[C:21](=[O:41])[C:22]2([CH2:23][O:24][c:25]3[cH:26][c:27]4[c:28]([cH:33][c:34]32)[O:29][CH2:30][CH2:31][O:32]4)[c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21.[NH:42]1[c:43]2[c:44]([cH:45][cH:46][cH:47][cH:48]2)[C:49]2([CH2:50][O:51][c:52]3[cH:53][c:54]4[c:55]([cH:56][c:57]32)[CH2:58][CH2:59][O:60]4)[C:61]1=[O:62]>>[CH2:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][o:8][n:9]2)[cH:10][cH:11]1)[N:20]1[C:21](=[O:41])[C:22]2([CH2:23][O:24][c:25]3[cH:26][c:27]4[c:28]([cH:33][c:34]32)[O:29][CH2:30][CH2:31][O:32]4)[c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21

Participants

5

Reactant 4

HCID 1419172-(Bromomethyl)tetrahydro-2H-pyranHCID 27355875-(Bromomethyl)-2,1,3-benzoxadiazoleHCID 58224164Spiro[furo[2,3-g]-1,4-benzodioxin-8(7H),3'-[3H]indol]-2'(1'H)-one, 2,3-dihydroHCID 592633545,6-dihydro-2H-spiro[benzofuro[6,5-b]furan-3,3'-indolin]-2'-one

Product 1

HCID 593523221'-(2,1,3-benzoxadiazol-5-ylmethyl)-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-951054b079d64fe5a92acf4e5cbc2680
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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