Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 306929Generated: October 27, 2026

Tetrahydrofuran → tert-Butyl 4-(4-chloro-2-(hydroxymethyl)phenyl)-4-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/306929

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant(2-Bromo-5-chlorophenyl)methanolHCID 23363134—
ReactantButyllithiumHCID 178418339—
Producttert-Butyl 4-(4-chloro-2-(hydroxymethyl)phenyl)-4-hydroxypiperidine-1-carboxylateHCID 57889172—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-85a1368df02c48ddb9723f6ff0b81886
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)