Dimethyl Sulfoxide → N2-(3-Ethynylphenyl)-N4-(3-quinolinyl)-2,4-pyrimidinediamine

HRID 307002Notes

Reaction equation

HRID 307002 reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]1.[CH3:28][S:29]([CH3:30])=[O:31].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][c:9]2[cH:10][n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]3[cH:18]2)[n:7]1.[Cl:32][CH2:33][Cl:34]>>[c:2]1([NH:24][c:23]2[cH:22][c:21]([C:19]#[CH:20])[cH:27][cH:26][cH:25]2)[n:3][cH:4][cH:5][c:6]([NH:8][c:9]2[cH:10][n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]3[cH:18]2)[n:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 104682Benzenamine, 3-ethynyl-HCID 22326846(2-Chloropyrimidin-4-yl)quinolin-3-ylamine

Product 1

HCID 9945755N2-(3-Ethynylphenyl)-N4-(3-quinolinyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-445b88dd6a974ed99cb8b892d66ad799
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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