HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophosgene → HCID 178440816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophosgene | HCID 10040 | — |
| Reactant | 3-tert-Butylaniline | HCID 79334 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 178440816 | HCID 178440816 | — |
Reaction Steps
To 3-(tert-butyl)phenylamine in acetone at 0° C. was added sodium bicarbonate (2 eq) and thiophosgene (2 eq). The mixture was brought to ambient temperature and concentrated and partitioned between ethyl acetate and water. The organic layer was dried with sodium bicarbonate and sodium sulfate and concentrated to yield 3-(tert-butyl)benzenisothiocyanate. MS: MH+=192.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423150B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-5c2f9b6dcb724652b0a751510608c005 |
| Source note | uspto-grants-2008_09 |